Trials of antidepressants for relapse prevention are confounded by withdrawal effects caused by the drugs.
New study finds that Medicaid enrolled youth were 14 times more likely to be on an antidepressant in 2014 than in 1987.
Researchers at Johns Hopkins test paroxetine on developing brain cells and discover numerous neurotoxic effects.
Researchers confirm that the suicide warning for antidepressants is justified by the evidence and that claims that the warning is harmful lack support.
A new update to the NICE guideline for depression suggests providers discuss long-term, severe antidepressant withdrawal symptoms.
A new review, published in BMJ Evidence-Based Medicine, concludes that antidepressants should not be used as the risks outweigh evidence for benefits.
Researchers critique the German S3 guidelines for depression promoting antidepressants.
A new study found that having been prescribed an antidepressant previously was associated with an increased risk of depressive relapse.
The addition of fluoxetine to CBT did not further reduce depressive symptoms in young people with moderate-to-severe depression.
A new study suggests that taking antidepressants impairs empathy, while the experience of depression itself does not.
Throughout the past two decades, studies have warned of increased suicide rates in those taking antidepressants, especially in children and adolescents. Researchers also documented...
People who take anticholinergic drugs, such as antidepressants and antipsychotics, are at a 50% higher risk of dementia.
Recent claims about antidepressant effectiveness have been based on misleading statements and misunderstandings of the science.
Researchers, publishing in Toxicology Research, review the evidence that antidepressant exposure in the womb is linked to autism spectrum disorders (ASD) in humans.
Researchers experimenting on mice found that exposure to fluoxetine (Prozac) in utero resulted in behaviors considered in animal studies to be analogous to autism in humans.
New study finds that antidepressants may negatively impact recovery after psychiatric hospitalization.
Dr. Vance Trudeau discusses his study's finding that antidepressants may have far-reaching, adverse effects that last up to three generations.
Study finds combining mirtazapine with an SSRI or SNRI is not clinically effective for improving depression in primary care patients who remained depressed after taking an SSRI or SNRI.
The researchers found that although antidepressants had a slight short-term effect on reducing the likelihood of depression diagnosis, there was no long-term improvement, nor any improvement in motor functioning.
Researchers question the overstated results of a large antidepressant meta-analysis and point to cultural pressures to turn to these drugs for a quick fix.
Researchers challenge the recommendation of starting two antidepressants simultaneously to increase preventative effects against suicide.
An international group of researchers, including several with financial ties to manufacturers of antidepressants, explore possible explanations for why long-term users of antidepressants become chronically depressed.
A new as-yet-unpublished trial of duloxetine (Cymbalta) for fibromyalgia has presented more evidence of suicidal events in teens.
Reanalysis of the original primary outcome measure in the STAR*D study suggests STAR*D findings inflate improvement on antidepressant medication and exclusion criteria in conventional clinical trials results in overestimation of antidepressant efficacy.
A new article in BMJ Evidence-Based Medicine addresses common misinterpretations of the efficacy research on antidepressants.